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Rapid Access to Preventive Intervention Development (RAPID) Program

Projects and Investigators

FY 2005 Projects

Washington University School of Medicine

Objective

Anti-tumor B (ATB), Chinese herbal mixture of six plants, for prevention of lung and upper aerodigestive tract tumors

Program Description

ATB has exhibited chemopreventive activity in animal models of lung cancer and in previous clinical studies in smokers with bronchial or esophageal dysplasia. The initial RAPID support may include:

  • Development of standardized ATB mixture for use in preclinical and clinical studies
  • Preclinical toxicological and pharmacological testing
  • Isolation, identification, and characterization of key components.

Contact Information

Dr. Ming You, M.D., Ph.D.
Washington University School of Medicine
St. Louis, MO
Tel: (314) 362-9294
Fax: (314) 362-9366
E-mail: youm@msnotes.wustl.edu