Projects and Investigators

FY 2000 Projects

Rutgers, The State University of New Jersey

Objective

Evaluation of farnesol and geraniol in human pancreative cancer.

Program Description

Investigators will conduct clinical testing of farnesol and geraniol in human pancreative cancer. Pancreatic cancer is rapidly growing and highly lethal. An average survival is less than 12 months and present chemotherapy extends survival by only few months. Farnesol and geraniol are found at low levels in several foods and essential oils and have been found to be potent inhibitors of human pancreatic tumor cell growth in vitro and pancreatic tumor growth in hamsters in vivo. RAPID support will include:

• Mutagenicity and short term preclinical toxicity testing,
• In vivo screening and efficacy testing,
• GMP synthesis, formulation, packaging, IND support, and
• Phase I studies.

Contact Information

Harold Newmark
Rutgers, The State University of New Jersey
New Jersey
Tel: 732-445-3400, ext. 242
Fax: 732-445-0687