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Rapid Access to Preventive Intervention Development (RAPID) Program

Projects and Investigators

FY 2006 Projects

University of Wisconsin

Objective

Pentamethylchromanol as a Novel Chemopreventive Antiandrogen and Antioxidant to Prevent Prostate Cancer Progression

Program Description

2, 2, 5, 7 ,8-pentamethyl-6-chromanol (PMCol) combines two mechanisms of action, anti-androgenic and antioxidant, which have a potential utility for prevention of prostate cancer as shown in preliminary preclinical studies. The initial RAPID support may include:

  • cGMP manufacture for preclinical studies and
  • Preclinical toxicological and pharmacological testing.

Contact Information

Glenn Liu, M.D.
University of Wisconsin
Madison, WI
Tel: (608) 265-8689
Fax: (608) 265-8133
E-mail: Gxl@medicine.wisc.edu