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Rapid Access to Preventive Intervention Development (RAPID) Program

Projects and Investigators

FY 2000 Projects

The Society for the Investigation of Early Pregnancy

Objective

Preclinical development of Developmental Peptides (DPs) as biopreventive agents.

Program Description

Investigators will conduct preclinical development of Developmental Peptides as biopreventive agents. Both embryogenesis and cancer are associated with rapid cell proliferation. Unlike cancer, embryogenesis is characterized by a delicate balance of proliferative and anti-proliferative processes. In preliminary studies, several peptide fractions from mammalian embryonic tissues have shown antiproliferative activity in cancer cells in cultures. RAPID support will include:

  • In vitro bioassay guided isolation,
  • Purification, and characterization of active fractions, and
  • In vitro and in vivo assay of more active fractions in rodent biopreventive tests.

Contact Information

Eytan Barnea
The Society for the Investigation of Early Pregnancy
New Jersey
Tel: 856-429-2699
Fax: 856-429-7414
E-mail: Barnea@earlypregnancy.org