Projects and Investigators

FY 2002 Projects

University of Arkansas for Medical Sciences

Objective

Preclinical development of mycochemicals in shiitake mushrooms.

Program Description

Investigators will conduct preclinical development of mycochemicals in shiitake mushrooms. Shiitake mushrooms (Lentinus edodes) have been described as having various medicinal properties, including chemopreventive ones. Studies in animal models support anti-cancer activity of Shiitake mycochemicals following oral consumption. RAPID support will include:

• growth and preparation of standardized log-grown Shiitake mushroom preparation;
• determination of dietary levels of mushrooms for subsequent studies;
• development of analytical methods for identification of mushroom mycochemicals;
• bioactivity based assays to identify mycochemicals;
• and correlation of mycochemicals in mushrooms, urine, and serum.

Contact Information

University of Arkansas for Medical Sciences
Tel: 501-320-2785
Fax: 501-320-2818
E-mail: BadgerThomasM@uams.edu