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Nutritional Science Research Group

Frontiers in Nutrition and Cancer Prevention: Online Series Presenters

Tuesday, May 17, 2011
1:00 – 2:30 pm EDT

Is Curcumin the Spice of Life? A Look at Cancer Prevention Evidence

Photo of Adhip PN Majumdar, PhD, DSc

Adhip PN Majumdar, PhD, DSc Exit Disclaimer

Professor, Wayne State University and Karmanos Cancer Institute
Senior Research Career Scientist
John D Dingell VA Medical Center
Detroit, MI

Dr. Adhip PN Majumdar earned his PhD in nutrition in 1968 from the University of London in the UK and his DSc in Gastroenterology from the University of Aarhus in 1984 in Denmark. He completed post-doctoral fellowships in molecular biology and biochemistry at the Clinical Research Institute and McMaster University, both in Canada. He is now a professor in the Division of Gastroenterology at Wayne State University and Karmanos Cancer Institute and is also a Senior Research Career Scientist at the John D. Dingell VA Medical Center in Detroit. Over the past 30 years, his work has focused on uncovering the biochemical and physiological pathways governing the growth of the gastrointestinal tract. He is particularly interested in elucidating the pathophysiology of age-related changes in the gastrointestinal mucosa that may lead to the development of malignancies. His team is extensively studying the chemopreventive and therapeutic effectiveness of several dietary agents including folic acid, resveratrol, and curcumin.

Dr. Majumdar has published over 175 original scientific articles in peer-reviewed journals and a multitude of book chapters and review articles, and holds four patents.

From Bench to Bedside: Curcumin Clinical Trial Results

Photo of Cherie-Ann Nathan, MD, FACS

Cherie-Ann Nathan, MD, FACS Exit Disclaimer

Director of Head and Neck Oncologic Surgery and Research
Feist-Weiller Cancer Center
Louisiana State University Health Sciences Center
Shreveport, LA

Cherie-Ann Nathan, MD, FACS completed her Otolaryngology/Head and Neck Surgery residency and fellowship in 1995 at University of California, San Diego. She is Professor of Otolaryngology/Head and Neck Surgery at LSUHSC, Shreveport, and Vice-Chairman of the Department. She is also Director of Head and Neck Oncologic Surgery and Research at the Feist-Weiller Cancer Center. She is a Surgeon-Scientist with a busy practice and leads an active clinical and basic science research team. Her main goal is to improve patient care, and she has an active translational research program funded by the National Cancer Institute focusing on Head and Neck Cancers. She is nationally and internationally recognized for her seminal work on molecular analysis of surgical margins. In 2011, she received NIH funding to continue her translational research on molecular markers from mTOR inhibitor clinical trials. In 2010, she received NIH funding for a phase 0 trial of curcumin in head and neck cancer (NCT01160302), and is now pursuing curcumin in other local application cancers.

Dr. Nathan has published extensively and has over 100 publications in peer reviewed journals and has authored textbook and encyclopedia chapters. She serves on several national committees and is a reviewer for numerous journals. In 2008, she was inducted into the Collegium ORLAS. Dr. Nathan serves on the program committee for the American Society of Clinical Oncology and is on the board of directors for the Head and Neck Cancer Alliance and the Board of Trustees for the American Head and Neck Foundation. She also serves as the chair for the American Head and Neck Society research committee. More recently the Board of Regents in Louisiana established the "Cherie-Ann Nathan Endowed Professorship in Otolaryngology/Head and Neck Surgery in 2010" initiated by grateful patients to honor her dedication and expertise.

Perspective on Future Research

Photo of Bharat B Aggarwal, PhD

Bharat B Aggarwal, PhD Exit Disclaimer

Professor and Chief of the Cytokine Research Section
MD Anderson Cancer Center Ransom Horne, Jr., Endowed Professorship in Cancer Research
Houston, TX

Dr. Bharat B Aggarwal earned his PhD in biochemistry in 1977 from the University of California, Berkeley, and did a postdoctoral fellowship in endocrinology at the University of California Medical Center, San Francisco. He then worked in a biotechnology company (Genentech, Inc.) for almost 10 years, where he isolated and determined the structure for the first time of TNF-a and TNF-b, two essential components of the immune system. The recombinant TNF-a that his group isolated was tested clinically in cancer patients for the first time in 1985 at The University of Texas MD Anderson Cancer Center in Houston, Texas. In 1989, Dr. Aggarwal accepted the position of Professor and Chief of the Cytokine Research Section at MD Anderson Cancer Center, where he currently holds the Ransom Horne, Jr., Endowed Professorship in Cancer Research. The primary focus of Dr. Aggarwal's current research is the role of inflammatory pathways in tumorigenesis and other diseases and their modulation by natural products. His group has identified several compounds from natural sources, some of which have reached the clinic for the treatment of patients. He has a special passion for anti-inflammatory phytochemicals from spices and traditional medicine. Dr. Aggarwal is a co-founder of Curry Pharmaceuticals and Charak International, both companies based on Natural Products.

Dr. Aggarwal has published more than 450 original articles in peer-reviewed journals and has also published invited reviews. He currently serves on the editorial boards of more than a dozen different journals, and he has edited 12 books and been granted 35 patents. Dr. Aggarwal also co-founded the International Society of Translational Cancer Research and organized conferences in India for that society. He has been invited to speak in more than 30 different countries and has delivered more than 300 lectures. Since 2001, Dr. Aggarwal has been listed as one of the "World's Most Highly Cited Scientists" by the Information Sciences Institute (ISI).

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