Key Programs

Prostate, Lung, Colorectal & Ovarian Cancer Screening Trial (PLCO)

PLCO News Updates

In addition to publications about the screening tests, PLCO supports studies of cancer causes, including genetic and epidemiologic research. For a complete list of scientific publications from PLCO, visit Publications.

• Top News
• Prostate Cancer
• Lung Cancer
• Colorectal Cancer
• Ovarian Cancer
• Studies of Cancer Causes

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Top News

• March 24, 2009: No Definitive Answers from Initial Results of PSA Screening Trials (NCI Cancer Bulletin)
• March 18, 2009: US Cancer Screening Trial Shows No Early Mortality Benefit from Annual Prostate Cancer Screening
  (NCI Press Release)
• March 18, 2009: New England Journal of Medicine Mortality Results from a Randomized Prostate-Cancer Screening Trial (PLCO) (Journal Article)
• March 18, 2009: New England Journal of Medicine Screening and Prostate-Cancer Mortality in a Randomized European Study (ERSPC) (Journal Article)
• March 18, 2009: New England Journal of Medicine Screening for Prostate Cancer — The Controversy That Refuses to Die (Editorial)
• July 26, 2001: PLCO Cancer Screening Trial Completes Recruitment

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Prostate Cancer

• March 24, 2009: No Definitive Answers from Initial Results of PSA Screening Trials (NCI Cancer Bulletin)
• March 18, 2009: US Cancer Screening Trial Shows No Early Mortality Benefit from Annual Prostate Cancer Screening (NCI Press Release)
• March 18, 2009: New England Journal of Medicine Mortality Results from a Randomized Prostate-Cancer Screening Trial (PLCO) (Journal Article)
• March 18, 2009: New England Journal of Medicine Screening and Prostate-Cancer Mortality in a Randomized European Study (ERSPC) (Journal Article)
• March 18, 2009: New England Journal of Medicine Screening for Prostate Cancer — The Controversy That Refuses to Die (Editorial)
• January 13, 2009: PLCO Update Suggests Positive Predictive Value of Prostate Screening Drops over Time (NCI Cancer Bulletin)
• January 1, 2009: British Journal of Urology International With annual prostate cancer screening, new cases are less advanced (PubMed Abstract)
• April 1, 2007: Researchers Discover Common Variations in Gene Segments that Increase the Risk for Prostate Cancer (NCI Press Release)
• March 22, 2005: PLCO Trial Publishes Baseline Findings (NCI Cancer Bulletin)
• March 15, 2005: Journal of the National Cancer Institute Prostate Cancer Screening in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial: Findings from the Initial Round of a Randomized Trial (PubMed Abstract)
• March 15, 2005: Prostate Cancer Research Results From the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: Fact Sheet
• March 10, 2005: Higher PSA Yields More Biopsies, Early PLCO Data Show (NCI Cancer Bulletin)
• February 16, 2005: Men More Likely to Get Prostate Cancer Biopsy Following High PSA Test Result (Press Release)
• May 20, 2002: Report from Large NCI Study Suggests PSA Testing Could Be Done at Longer Intervals for Men Who Choose to Test (Press Release)

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Lung Cancer

• December 2005: Journal of the National Cancer Institute Baseline Chest Radiograph for Lung Cancer Detection in the Randomized Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PubMed Abstract)

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Colorectal Cancer

• July 11, 2005: Colorectal Cancer Research from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: NCI Fact Sheet
• July 6, 2005: Journal of the National Cancer Institute
  Flexible Sigmoidoscopy in the PLCO Cancer Screening Trial: Results from the Baseline Screening Examination of a Randomized Trial (Pub Med Abstract)
• July 5, 2005: PLCO Publishes Sigmoidoscopy Results (NCI Cancer Bulletin)
• July 1, 2003: National Cancer Institute Trial Yields New Data on Colon Cancer Screening Test (Press Release)

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Ovarian Cancer

• November 15, 2005: American Journal of Obstetrics and Gynecology Ovarian Cancer Screening in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: Findings from the Initial Screen of a Randomized Trial (Pub Med Abstract)
• November 7, 2005: Ovarian Cancer Screening Using Ultrasound and CA125 Finds both Early and Late Stage Cancers, But Also Many False Positives

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Studies of Cancer Causes

• March 11, 2009: Researchers Find Abnormal Cells in the Blood Years Before Leukemia is Diagnosed (NCI Press Release)

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