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Trans-NIH Angiogenesis Workshop; May 20-21, 2013
  • Speaker Biosketches

    Portrait of Peter F. Carmeliet, MD, PhD

    Peter F. Carmeliet, MD, PhD
    (VIB Vesalius Research Centre, K.U. Leuven, Belgium)

    Dr. Peter Carmeliet is Director of the VIB — Vesalius Research Center, at the University of Leuven in Belgium. He graduated as Doctor in Medicine in 1984, and completed his Ph.D. in Medicine in 1989. After his return to Leuven in 1992, Dr. Carmeliet started his own research group with a focus on how blood vessels grow (angiogenesis) in health and disease. By developing transgenic mice lacking VEGF, he discovered that VEGF is a key player in angiogenesis. Dr. Carmeliet's findings have led to the (pre)clinical development of novel therapeutic strategies for angiogenic diseases. He also showed that PlGF is a disease—restricted candidate in many angiogenic disorders and tested the therapeutic potential of anti-PlGF.

    In 2001, Dr. Carmeliet documented that low VEGF levels in mice and in humans cause motorneuron degeneration, similar to patients suffering the incurable disease amyotrophic lateral sclerosis (ALS). These studies not only provide evidence for a role of VEGF in neurodegeneration, but also opened therapeutic opportunities, which have resulted in clinical tests of VEGF delivery for ALS patients. The Carmeliet lab is currently studying how endothelial cells change their metabolism during vascular branching and exploring the therapeutic potential of targeting endothelial metabolism for anti-angiogenic strategies.

    Dr. Carmeliet published over 480 research articles and reviews, his achievements have been recognized by several International Honors and Awards.

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Workshop Organizer: NIH

NCI:Nancy Emenaker, PhD, RD
Suzanne Forry-Schaudies, PhD
NHLBI: Yunling Gao, MD, PhD
NIDDK: Teresa Jones, MD

NIH - National Institutes of Health: Turning Discovery Into Health

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