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Frontiers in Metabolomics for Cancer Research

Meeting Date

October 24-25, 2005

Meeting Location

DoubleTree Hotel and Executive Meeting Center
1750 Rockville Pike
Rockville, MD 20852

Meeting Objectives

The purpose of this workshop is to identify gaps for the application of metabolomics for cancer research and to disseminate the information on metabolomics and its potential application for cancer research. Specific aims for the workshop include;

  • Identify issues with the use of metabolomics, including measurements in cells or body fluids;
  • Review metabolomics arrays, spectroscopic profiles, and other metabolites-based phenotyping in relation to its application for patients, stratification for responders and non-responders to dietary components, drugs, and toxic agents;
  • Discuss what information metabolomics provides over that provided by genomics and/or proteomics; and
  • Assess the current state of metabolomic technologies as they relate to cancer prevention research.


  • National Cancer Institute
    • Division of Cancer Prevention
    • Division of Cancer Biology
    • Division of Cancer Epidemiology and Genetics
    • Center for Cancer Research
  • NIH Office of Dietary Supplements

Meeting Materials


Name Position Presentation (ppt)
Sudhir Srivastava, PhD, MPH Chief, Cancer Biomarkers Research Group Metabolomics: An Untapped Frontier (ppt, 161kb)
John Milner, PhD Chief, Nutritional Sciences Research Group Can Metabolomics Provide Clues about the Progression of Disease (ppt, 430kb)
Padma Maruvada, PhD
Young Kim, PhD
Program Director, Cancer Biomarkers Research Group Director, Nutritional Sciences Research Group Frontiers in Metabolomics for Cancer Research (ppt, 85kb)
Meeting Objectives and Sponsors (ppt, 44kb)
Jules Griffin University of Cambridge Department of Biochemistry What is Metabolomics/Metabonomics (ppt, 3.6mb)
Stephen C. Brown Research Fellow, Chemistry, Esperion Therapeutics Technologies for Metabolics Profiling (ppt, 646kb)
Henri Brunengrager Case School of Medicine MIT School of Engineering Pathway Discovery via the Association of Metabolomics and Mass Isotopomer Analysis (ppt, 645kb)
Sybille Mazurek Institute of Biochemistry & Endocrinology, Veterinary Faculty, University of Giessen A Crossroad to Tumor Metabolome: Pyruvate Kinase Type M2 (ppt, 11.2mb)
John Griffiths Cancer Research UK Biomedical Magnetic Resonance Research Group, Department of Basic Medical Sciences, St George's Hospital Medical School Metabolomics by Magnetic Resonance: From Molecules to Man (ppt, 1.9mb)
Leo Cheng Massachusetts General Hospital Harvard University Metabolomic Profiling of Human Cancer With Ex Vivo Tissue MR Spectroscopy (ppt, 38mb)
Paul Lee, MD David Geffen School of Medicine at UCLA - Los Angeles Biomedical Research Institute at Harbor-UCLA Glucose Metabolics Phenotypes in Cancer (ppt, 983kb)
Edward A. Dennis Departments of Pharmacology and Chemistry/Biochemistry University of California, San Diego Lipidomic Profiling Eicosanoid Changes in Carcinogenesis (ppt, 7.6mb)
Risto A. Kauppien University of Birmingham, U.K. MR Spectroscopic Analysis of Tumour Metabolic Phenotype Changes in Response to Therapy (ppt, 21.9mb)
Zoltan N. Oltvai Department of Pathology University of Pittsburgh School of Medicine Other models to understand the cancer cell metabolic flux (ppt, 12.5mb)
Rima Kaddurah-Daouk,PhD Duke University Medical Center Metabolomics in the study of CNS Disorders: Early Lessons Learned (ppt, 5.9mb)
Michael N. Liebman, PhD Executive Director Windber Research Institute A Systems Approach to Breast Cancer (ppt, 2.1mb)
Bruce Kristal and Gilbert Omenn Application of Metabolomics in Understanding Tumor Cell Behavior (ppt, 28kb)
Young Kim, PhD
Padma Maruvada, PhD
Director, Nutritional Sciences Research Group Program Director, Cancer Biomarkers Research Group Future Directions (ppt, 44kb)
Thank You (ppt, 42kb)

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