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Molecular Targets for Dietary Prevention of Prostate Cancer

Agenda

June 16, 2000


8:30 - 8:45 am Welcome Carolyn K Clifford
8:45 - 8:50 am Introduction to Workshop Peter Greenwald

Studies of Diet and Prostate Cancer in Humans
Moderator: Carolyn K Clifford
8:50 - 9:10 am Epidemiological Evidence for Diet and Prostate Cancer Relationship Meir Stampfer
9:10 - 9:30 amOngoing Clinical Trials of Prostate Cancer Howard Parnes

Experimental Evidence Supporting Specific Dietary Factors
Moderator: Young S Kim
9:30 - 9:55 amDietary Lipids David Heber
9:55 - 10:20 am Arachidonic Acid and Cell Proliferation Charles E Myers
10:20 - 10:40 am BREAK
10:40 - 11:05 am Soy Products and Genistein Stephen Barnes
11:05 - 11:30 am Vitamin D Robert H
Getzenberg
11:30 - 11:55 am Molecular Markers for Prostate Cancer Angelo M De Marzo
11:55 am - 12:20 pm Transgenic Animal Models Jeffrey E Green
12:20 - 1:20 pm LUNCH

Panel Discussion and Recommendations for Future Directions
Moderator: John Milner
Panels:
Leland W Chung
Meir Stampfer
Stephen Barnes
Samson T Jacob
Robert H Getzenberg
Angelo M De Marzo
Barbara C Pence
David Heber
Jeffrey E Green
Harold Adelman
Charles E Myers

1:20 - 3:30 pm Future Directions for Nutrition - Prostate Cancer Prevention Research
  1. Which nutritional interventions appear to be most promising to decrease prostate cancer risk?
  2. Which high risk groups should be targeted?
  3. Which potential dietary and/or prostate specific molecular markers should be explored as intermediate end point measurements?
  4. Which potential dietary and/or prostate specific molecular markers should be explored as intermediate end point measurements?
    1. Which molecular targets and gene - nutrient interactions should be investigated?
    2. Which of the prostate cancer animal models are most appropriate for nutrition-prostate cancer prevention research? What are the sources and the availability of these models?
  5. What can the NCI do to enhance interdisciplinary collaborations?
3:30 pm ADJOURNMENT


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